Building a first-class bay district and a star city group is a very important strategic goal for the development in Guangdong，Hong Kong and Macao. Based on the 100-year meteorological observations and simulation results of regional climate models in the Great Bay District，this work systematically analyzes the characteristics of climate and ecological environment，the facts of climate change and extreme events，meteorological disasters and climate risks，climate trends in the next 30 years，challenges to the climate environment and climate change adaptation. Results show that the Great Bay District is warm and rainy，with various climate types，frequent meteorological disasters and good vegetation conditions. However，it is located in a vulnerable region with low latitude climate system，and its unique advantages coexist with climate risks. In the past 60 years，the climate in the Great Bay District has been warm and humid；the short-term precipitation intensity is strong，the landing typhoon intensity is strong，the sea level rises rapidly，the meteorological disaster is serious，the climate risk is high，the disaster and risk will continue in the next 30 years. Facing the needs of disaster prevention and mitigation，and climate change adaptation，we must take active actions to rationally use climate resources，improve the risk management capabilities of meteorological disasters，and strengthen climate change adaption urban construction.