In 2023-2024，the United States continues to push forward its new strategy in Middle East and follows up with series of policies to support it，while Russia，China and other non-Western powers have deepened their relations with the Middle East countries，especially with the Arab countries. After the outbreak of the new round of Palestinian-Israeli conflict，the United States has spared no effort to support Israel，the major powers in Europe has also supported Israel yet with some differences from the the United States. Russia and China focuses on building international consensus and actively promotes a ceasefire to stop the war between Israel and Hamas. At the same time，the détente among Middle Eastern countries has continued to advance on multiple tracks. However，the détente has had a limited effect on resolving regional conflicts because it has failed to address many of the deep-rooted factors that driving the conflicts in this region. The outbreak of this new round of the Palestinian-Israeli conflict is a notable manifestation of it. Under the Palestinian-Israeli conflict lasting，the risk of escalation of the conflicts in Middle East has increased，and the inherent contradictions of the U.S. new strategy in Middle East have come to the forefront，with serious damage to its international credibility and national image. Looking ahead，the Middle East’s position in U.S. global strategy may increase，the strategic autonomy of Middle Eastern powers and their policy of “multi-directional diplomacy” may become more prominent，and China has planed a new blueprint for developing its relations with the Arab countries.