Industry is the foundation of a country，the tool of prosperity，the road to prosperity and the foundation of a powerful country，and industry is the leading force of the national economy. Without the high-quality development of industrial economy，there will be no modern economic system and no high-quality development of China’s economy. Based on the existing research results，this study constructs the evaluation index system of high-quality industrial economic development in the central region，including innovation development，coordinated development，green development，open development and shared development，totaling 16 specific evaluation indicators. Using the relevant statistical data，the index weight is determined by subjective and objective methods，and the high-quality development level of industrial economy in six provinces in central China is measured. The evaluation results show that the ranking of the comprehensive evaluation of high-quality industrial economic development in the central region from high to low is Anhui，Hunan，Hubei，Jiangxi，Henan and Shanxi. The order of innovation and development is consistent with the order of comprehensive evaluation；The order of coordinated development is Jiangxi，Henan，Anhui，Hubei，Hunan and Shanxi；The ranking of green development is Hubei，Hunan，Henan，Anhui，Jiangxi and Shanxi；The ranking of open development is Jiangxi，Anhui，Hunan，Hubei，Henan and Shanxi；The ranking of shared development is Anhui，Hubei，Hunan，Jiangxi，Henan and Shanxi. Finally，the report proposes that we should focus on five development concepts and take various measures to promote the high-quality development of regional industrial economy in a coordinated manner.