At present，the phenomenon of counter-globalization is serious. As an important representative of emerging market countries and developing countries，the BRICS countries have become an important force in global economic governance. The upgrading of cooperation between the BRICS countries in terms of economic and trade finance，political security，and humanities exchanges is essential for common development，multilateralism，and maintaining global fairness and justice. Taking humanistic characteristics as a breakthrough to analyze the advantages and disadvantages of the conditions of cooperation，it is more likely to produce subtle influences and quiet results for the BRICS cooperation，and is more conducive to the realization of inclusive development and seeking common ground while reserving differences. Due to the geographical，historical，religious，ethnic，and demographic differences of the BRICS countries，their humanistic characteristics are also diverse. This paper clarifies the beneficial and obstructive humanistic characteristics of between Russia，India，Brazil，South Africa and China and the factors that may potentially affect the BRICS cooperation. It is hoped that the humanities will find an efficient way of cooperation in BRICS.