China has long been building a strategic relationship of friendship and partnership with Thailand. Since the signing of the trade agreement in March 1978，the Sino-Thai bilateral trade volume has been on the rise year by year，which has been $758.86 billion in 2016. The advent of the era of e-commerce promotes the cooperation and development of cross-border business between the two countries. For instance，Top Grade of Thailand and Yunnan Yimin Food Tesco E-commerce launched the platform Food Tesco，Thaicn. Net and CCIC Group established the e-commerce website Thailand No. 1 Store. Due to the difference of situations between China and Thailand，and the lack of strategic thinking during the cross-border cooperation，there exist serious problems in the operation mode，technical level and service quality of cross-border e-commerce platform.

On the basis of a discussion about the implementation status of Sino-Thai cross-border e-commerce，this paper exerts a PEST analysis on its macro environment of strategic cooperation. Then，we put forward the construction paths and contents of Sino-Thai strategic cooperation platform for cross-border e-commerce，as well as the construction principles and strategies. This paper aims to solve the problems of Sino-Thai cross-border e-commerce and promote a healthier and more sustainable development of economic and trade cooperation between China and Thailand.