When the long years of the Ming-Qing conquest in the 17th century drew to a close，the Chinese coastal resistance force became almost the last active group on the Ming side. Expecting to meet more and more severe pressure from the Manchus，the leader of the resistance forces，Ming loyalist warlord Coxinga，launched an attack on the neighboring Dutch colony on Taiwan in 1661 and laid siege to the Dutch Fort Zeelandia for nine months，intending to grab this colony to support his further ambitions. The Dutch lost the battle and had to surrender the fort in February 1662. The Dutch soldiers who deserted during this battle then continued their careers under the Coxinga（Zheng）regime，while a small group of Dutch officials and families who surrendered during the siege remained in Taiwan. They were stuck there because they missed the monsoon season in 1662，and were again prevented from leaving when the war between the Zheng forces and Dutch resumed in 1663. One of the deserters，Hugo Rozijn，survived under the Zheng regime on Taiwan for more than 21 years. He established a family and was hired as a translator and medical practitioner. When the English East India Company made contact in Taiwan for trade in 1670，he passed messages from the Dutch prisoners to the English merchants. Later when the Zheng regime fell because of the Manchu attack in 1683，the Dutch prisoners were released，and Rozijn applied with the VOC（Dutch East India Company）asking to return with his two sons to Batavia as a ship surgeon. He then served on the Company’s ship again，sailing from Batavia to Japan，China and the coast of Bengal in the 1690s. This brief story of Hugo Rozijn，including his acquaintances among the deserting soldiers，those prisoners who were unable to leave，English merchants and Jesuits in China，offers a brief glimpse of cross-cultural encounters in war，trade and marriage across different East Asian waters and to the margins of the Indian Ocean. This story also roughly matches a Taiwanese folk tale that may have lasted in oral form for more than 250 years. This shows how，at a personal level，the trend of globalization since that time had begun to intensify such cross-cultural encounters through maritime interactions，and how such experiences may have been stored in collective local memories，even though the traditional Chinese historiography fell short in this case.