The Yangtze River channel is the most important thing in the development of China's land space, and has an important strategic position in the overall pattern of regional development in China. In this paper, Jiangsu Province as the main body, the Yangtze River economic belt development strategy for in-depth study. Firstly, the docking status and role of the Yangtze River Economic Belt strategy in Jiangsu exposition, pointed out that Jiangsu is located in the "leading" and "Shanghai dragon waist" between Wuhan and the Yangtze River economic belt, is the dragon "dragon neck", is to undertake the "leading", coordinated control of "Dragon waist" and "tail" of the center. Is the natural link to the East and the west, can effectively achieve the "opening to the west" and "river development" "coastal development and cooperation; secondly to docking the Yangtze River Economic Belt strategy in the development of Jiangsu's strategic positioning is analyzed, pointed out that Jiangsu province is deepening reform and opening up, leading to the national" two way "the strategy of innovation driven hub, leading the transformation and upgrading of the model area, an important global advanced manufacturing industry and modern service industry center and regional coordinated development demonstration area, demonstration area of finance opening and the construction of ecological civilization Pilot area; and then elaborate on the Yangtze River Economic Belt strategy in Jiangsu development path selection and countermeasures, including strengthening the regional economic linkage along the Yangtze River in Jiangsu, enhance regional integration functions, such as eight aspects.