This paper aims to study Shanghai’s resilience to water disasters under the condition of climate change，and the cooperation in the Yangtze Delta to enhance such resilience of Shanghai，and the suggestions to improve such cooperation will be put forward. Under thebackground of climate change，the water disasters facing Shanghai mainly include salt tide intensified by upstream water reduction in dry season，flood caused by typhoon + rainstorm + over-abundant upstream water in wet season and shortage of clean water intensified by inputted pollution. As to the water environment cooperation between Shanghai and neighboring jurisdictions，coordinating agencies have been established，united actions have been taken in law enforcement and emergency management；but such cooperation is short of economic instruments，and there is little or even no cooperation in emergency management of salt tide，wetland construction and sponge city construction. If Shanghai can overcome the shortcomings where there is little or no cooperation，innovate and adopt various economic instruments in the existing Yangtze Delta water management cooperation，and make deep-insight research on diverting ships on and pollution in the Taipu River，it will be greatly helpful to improve Shanghai’s resilience to water disasters under climate change.