In October 20, 2011, the death of Al-Qaddafi not only made Libya into an uncertain state of chaos, but also the integration process of the African continent into a turning point of uncertain prospects. Qaddafi during his lifetime is a mixed character, it now seems possible to the coffin, but the difficulty is big, because Qaddafi's life and political career ended in this way, both in Libya's current political atmosphere or in the international community when under the atmosphere of public opinion, it is difficult to his merits and demerits in Libya in the process of historical development of give an objective and fair evaluation, which, of course, is not the problem this paper concerned with. This paper is focused on the core problem is that Qaddafi for Africa reunification devoted a lot of enthusiasm and efforts, in some extent, people talking about African integration, especially when talking about the development of the African Union, can not help but think of and reference to Qaddafi, then such a thing of African integration industry key figures in the death, what kind of impact will be produces on the subsequent development of Au and the future of African integration?