As an integral part of South-South cooperation，China-Africa economic and trade cooperation holds significant strategic importance for promoting economic development in Africa and deepening China’s opening-up policies. This report systematically explores the historical evolution，current characteristics，and future development trends of bilateral economic and trade cooperation between China and Ghana. Firstly，it provides a multidimensional analysis of Ghana’s national conditions，offering a theoretical foundation for understanding the context of China-Ghana economic and trade cooperation. Secondly，the report reviews the development trajectory of China-Ghana cooperation，summarizing the main features of the cooperation model，including the evolution of trade structures，investment areas，and cooperation mechanisms. Building on this，the report delves into the core challenges facing China-Ghana economic and trade cooperation，encompassing structural economic difficulties in Ghana，external economic shocks，weaknesses in industrial chains，corporate investment risks，and insufficient stability in policies and regulations. Finally，the report proposes targeted policy recommendations，including optimizing Ghana’s investment environment assessment system，improving the bilateral investment legal framework，promoting deep industrial chain integration，and strengthening financial cooperation and risk prevention mechanisms. These recommendations aim to provide theoretical support and practical pathways for the high-quality development of China-Ghana economic and trade cooperation.