With the development of cross-border e-commerce，“Silk Road E-Commerce” has become a key part for China to build national trade with “the Belt and Road”. At present，China has signed bilateral e-commerce cooperation memorandums and established cooperation mechanisms with 33 countries，forming a global cross-border e-commerce ecological chain. In the context of the continuous acceleration of global e-commerce development，the scale of cross-border e-commerce market in the countries of “the Belt and Road” has grown rapidly，the innovation of the “Silk Road E-Commerce” model has continued to accelerate，and the conditions of the basic development have been constantly optimized. The report considers that “Silk Road E-Commerce” presents characteristics such as the continuous expansion of cooperation scope，the growth policies，the mutual benefit cooperation models，and the institutional openness. However，“Silk Road E-Commerce” also faces many challenges，including the logistics network infrastructure needs to be improved，the corporate compliance awareness and the localization level needs to be improved，the cross-border e-commerce laws and regulations are different，there are multicultural and language barriers，and the restrictions of destination countries trade. In the future，it should accelerate the construction of infrastructure，optimizing the cross-border payment processes，establishing a unified legal system of e-commerce，strengthening the localized training of cross-border talents，so as to better achieve the higher quality development of “Silk Road E-Commerce”.