This paper focuses on the policy evolution of the U.S.global communicative strategy since the 21st century，especially changes in the U.S.government regulatory system with the adjustment of its global communicative strategy，in an effort to provide inspiration and reference for strengthening China’s strategic planning and system building for international communication. According to the study，the key policy and institutional changes of the U.S.global communicative strategy present three outstanding features：first，it strengthens the construction of the global communicative system featuring “top-level design and multi-agent collaboration.” This clarifies the objective，nature，agent composition，and action mechanism of the global communicative strategy at the federal level，and is even good at coordinating political，diplomatic，economic，military，media，cultural and other subjects through the leadership of high-level committees and think tanks. Second，it strengthens the closed-loop layout of global communicative ecology featuring “soft power and hard power.” The U.S.federal government attaches great importance to “soft power” such as global information dissemination and cultural exchanges，while promoting the development of critical information infrastructure at home and abroad at a very high level and with great efforts to provide a solid foundation for global communication in the Internet era. Third，it strengthens the global communicative link design of “issue setting + effect evaluation.” This focuses on the control of global issues from the source and the evaluation and feedback of communication effects，so as to adjust and optimize global communicative strategy.