Faced with the increasingly severe situation of drug control，countries have explored drug crime governance systems such as“one body，two borrowing，two cutting”，“grid based”，and“multidisciplinary comprehensive”，but all of them have certain limitations.The introduction of game theory provides a new approach：Based on the analysis of the drug crime governance situation in B village of G province，a game platform is built to discover that the game subjects are prone to information asymmetry during the formation stage，which can lead to problems such as“adverse selection”；In the decision-making stage，the crime scene is the key factor affecting criminal decision-making；In the final stage，relying solely on criminal deterrence or welfare policies cannot obtain the optimal solution of the game equilibrium.To eliminate governance gaps，a drug governance system is constructed from the stages of“in the future，in the present，and already”.Firstly，it promotes the symmetric and full flow of information，and encourages criminal decision-makers to make“positive choices”；Secondly，control the temporal and spatial factors，strictly control the crime scene，and prevent the formation of objective drug crimes；The third priority is to control demand，suppress drug abuse，reduce the demand market，control drug substitutes，and strengthen anti money laundering cooperation，thus forming a three-level dynamic comprehensive governance system for drug crimes.