In 2023，the types of drugs and how they were manufactured，trafficked，and abused became increasingly diverse and complex.Asia，Africa，and Latin America，where regional instability existed，particularly suffered from the scourge of drugs.Drug problems pose a serious threat to sustainable development，making international cooperation in the fight against drugs increasingly important.To respond effectively to the challenges，the United Nations Office on Drugs and Crime，in conjunction with other international drug control agencies and their member States，developed various drug control programs，including the Regional Programme for South Asia（2023-2027）.In addition to regional drug control programs，many governments have strengthened their domestic drug control efforts and implemented stricter drug policies.The Chinese government has also made positive efforts，not only to strengthen the management of drugs such as etomidate and modafinil but also to reactivate the Narcotics Control Cooperation Working Group with the United States government.In the face of the new situation of the global drug issue and the new challenges it brings，all countries in the world need to actively respond to the challenges，further build consensus，and deepen international narcotics control cooperation to achieve effective governance of the global drug problem.