During the ten years of the Syrian crisis from 2011 to 2021，Western countries’ sanctions on Syria have gone through three stages：frequent sanctions-relativestagnation-and gradual increase. Various forms and wide-ranging sanctions are aimed at overthrowing the “anti-American Assad regime”. However，with the stabilization of the political situation in Syria in 2021，sanctions not only failed to overthrow Assad regime，but also plunged most Syrian people into a series of social crises. Therefore，sanctions not only aggravate the social crisis in Syria，but also become a stumbling block for Syria and the international community to participate in post-war reconstruction. The sanctions imposed on Syria by American and Western countries will become a major obstacle for Syria to restructure its economy.