In 2022，the situation in the post-Soviet space experienced a sharp deterioration. After the escalation of the Ukraine crisis，Russia and Ukraine broke off diplomatic relations，and their relationship has completely moved to the opposite side. In terms of the Ukraine crisis，Belarus is most deeply tied to Russia. Even not directly involved in the conflict，it stands firmly behind Russia，and the relationship between the two countries has further deepened in the crisis. Central Asian countries maintain a neutral attitude. They neither openly support Russia nor join the sanctions against Russia. At the same time，these countries provide humanitarian assistance to Ukraine. Affected by the crisis，the instability in the Transcaucasia has increased，and the Nagorno-Karabakh conflict resurfaces. Russia pays close attention to the situation of the Nagorno-Karabakh region and hopes to achieved peace in the region through negotiations. Moldova is deeply influenced by the US and the West，and the country’s foreign policy shows a certain degree of swing. Russia pays close attention to the diplomatic statements of Moldova，and strives to make it controllable. While developing bilateral relations with countries in the post-Soviet space，Russia actively promotes multilateral cooperation within the frameworks of three major organizations in the post-Soviet space，the Commonwealth of Independent States，the Collective Security Treaty Organization，and the Eurasian Economic Union.