Synergetic development between regions needs synchronous regional synergy legislation. Regional synergy legislation is a new legislative mechanism based on the traditional local legislation，and it is not only an important guarantee for the coordinated development of regional economy，but also an inevitable requirement of the modernization of national governance. However，there is concern about the constitutionality of regional synergy legislation in China，and its process has also been slowed down by the conflicts of interests among regional subjects within the region. In addition，the lack of experience in relevant legislative cooperation also puzzles legislators. In the face of the dilemma，it is necessary to affirm the legislative status of regional synergy legislation in our country’s constitution and laws，value the pioneer experience of regional synergy legislation，break the local barriers of regional synergy legislation，and construct the interest compensation mechanism of regional synergy legislation，in order to achieve a new breakthrough.