The nuclear fuel cycle industry is a high-tech strategic industry and the foundation for the development of nuclear energy. In 2021，Nuclear fuel industry keeps stable production and supply，continuously increase the industrial scale，and further consolidate the support capability while against the COVID-19. Important progress has been made in uranium exploration，mining and metallurgy technology. Continuous improvement has been achieved for the quality development of uranium enrichment industry. The R&D and industrialization of self-owned nuclear fuel brand has been accelerated. Important achievements in the construction of LLW centralized disposal sites has been made. New breakthroughs for the construction of underground laboratories for high-level radioactive waste has been achieved.