Since the reform and opening up，Henan science and technology system reform has experienced four stages，entered the comprehensive deepening period，The third plenary session of the 18th CPC national congress pointed out the direction of the reform of science and technology system，Henan must resolve transformation of scientific and technological achievements of management system，mechanism，incentive mechanism，environment and other problems，bold exploration，deepening the reform of science and technology system comprehensively，to make innovation-driven development strategy in the rise of central China，Henan revitalize，the prosperous common people strong province play a bigger role in the process.