With the COVID-19 epidemic still raging and major power competition on the rise，the world was struggling in 2021 to explore approaches to cooperation despite these negative impacts. International organizations took active measures to promote post-epidemic economic recovery and inclusive development. The Biden administration of the US was mobilizing allies on board for repositioning. The EU adjusted its foreign policy and China engaged itself in shaping neighborhood diplomacy to build a community of shared future for mankind. All economies are managing adaptation in the changing world proactively. At the same time，digital trade demonstrates strong resilience in its development during the epidemic and becomes an important growth engine for the global trade in services.