Russia’s drug situation is grim，is the important consumer market and transport channels of international drug production and trafficking activities. China and Russia have similar anti-drug concepts and regard drug prevention as an important direction of anti-drug work. Russia’s drug prevention work advocates multi-department，the whole society linkage，regard the youth as the key population of prevention education，emphasize the formation of “parents，school，society” three levels for the youth to form a voluntary anti-drug environment，and the implementation of a three-level prevention system. Russia’s drug prevention work experience has achieved more obvious results，to curb the phenomenon of adolescent drug abuse in Russia has a certain effect. The Russian experience can be used as a reference for the implementation of drug prevention work in China，early detection of high-risk adolescent groups and early intervention，and mobilization of the whole social forces to participate in drug prevention work.