The national and regional research in the new era should respond to the major strategic concerns of the country and focus on establishing key research areas and research directions from the “national level，regional level and global level”. Focus on the realization of theoretical achievements and paradigm innovation，and play a leading role in the construction of “Chinese School” with Chinese characteristics. In order to provide theoretical support for national decision-making，we should deeply study and judge the main characteristics，development trends and important influences of the relations among big powers in the era of big power competition. We will promote the one belt，one road，high quality development，and fully pay attention to and judge the development trend of small and medium-sized countries. This paper systematically reviews the favorable conditions and practical challenges of China’s regional cooperation，and summarizes the overall characteristics of regional integration. We should pay more attention to the non-traditional security field and strengthen the research on terrorism，climate warming，energy security and public health. We should seriously explore the effective path of global governance，contribute Chinese wisdom，provide Chinese solutions and show Chinese strength to promote the construction of a community of shared future for mankind.