Based on the current status of the Guangzhou industrial chain development，this paper，combining the path of the strengthening chain，along with interviews，analyses difficulties faced by private entities that many core technologies are owned by others，high-end manufacturing levels are relatively low，collaborative innovations are insufficient，basic research supports are insufficient，and that anti-risk capability are relatively low. This article proposes the optimization of private entity industry chains，establishing recommendations for responding to systematic risk long-term mechanisms.