In 2020，France was seriously affected by the COVID-19 epidemic. By the spring of 2021，France has become the most severely infected country in Europe. The epidemic has had a huge impact on France’s politics and economy，and various political parties have rearranged their election strategies in accordance with the epidemic. The peculiarity of the French political system has caused an intertwined game among various political institutions such as the President，the Prime Minister，the National Assembly，and the Senate，restraining French government ability to control the epidemic. Fortunately，the French administrative reform had increased local powers，and local organizations at all levels have shown their abilities in responding to the epidemic，providing new ideas for future administrative reforms. The French economy suffered a severe recession during the epidemic，and the government has taken numerous fiscal measures to alleviate the impact of the epidemic. The French government is trying to take the opportunity to rebuild the industrial production chain，but it still faces huge challenges. Despite the severe epidemic，the French people still took to the streets in 2020 to protest against the government’s bills to be passed in the National Assembly. One involves the reform of the pension system and the other involves the supervision over the police forces suspected of violent law enforcement. France has also experienced terrorist attacks by extreme Islamic forces in 2020. A series of “counter-measures” taken by the French government has triggered tensions and conflicts between France and Muslim countries. As a global power with big political influence in the world arena，France has stepped up its assistance to Africa during the epidemic and also strengthened its “Indo-Pacific strategy”. Although France has shown its presence in the Middle East through its special relationship with Lebanon，it is difficult for it to regain its special influence in the Middle East，due to its tension with Muslim countries.