Since 2020，the relationship between the United States and India has developed steadily. President Trump’s visit to India and the US-India “2+2” talks are the highlights of high-level interaction between the two sides. The relationship between the two countries has been upgraded to a “comprehensive global strategic partnership”. The strategic integration between the two countries in the Indo-Pacific region has further deepened. The military cooperation between the US and India has been deepening，and both sides have achieved certain achievements in signing cooperation agreements，military trade and joint exercises. Trump’s trade protectionism policy and India’s countermeasures have affected the smooth development of economic and trade relations between the two countries. However，the consensus between the two countries in the energy field has promoted the rapid development of bilateral energy cooperation. The U.S.-India cooperation under the Indo-Pacific Strategy is partly in response to China’s growing influence in the Indo-Pacific region.