The atmosphere of Sino-U.S. relation deteriorated further in 2020 due to the Trump administration’s escalating information warfare towards China. Against this backdrop，the Trump administration escalated its strategic competition with China in the fields of high technology，geostrategy，and ideology. The Chinese government has engaged in a tit-for-tat counter-measures in response，and the strategic competition between China and U.S. has escalated. The Trump administration actively deploys a comprehensive science warfare towards China，and in response，Chinese government elevated “indigenous innovation” to a new strategic height；The United States speeded up the integration of Taiwan into America’s Indo-Pacific Strategy，and the Sino-U.S. confrontations with respect to South China Sea and Taiwan has been escalating；In the ideological field，the Sino-U.S. struggles focused on Hong Kong and Xinjiang has become increasingly fierce. After the 2020 presidential election，strategic competition will remain the dominant theme in Sino-U.S. relation，but the Biden administration would adopt more multilateral approaches to compete with China. In the future，the form of strategic competition between China and the United States will be more complex and volatile.