In 2020，the United States continues to increase its strategic focus and commitment to Central Asia，releasing a new Central Asia strategy document. The new Central Asian strategy marks an important transformation of the past strategic paradigm of the United States. The essence of which is to compete with China as the main axis，and to shrink the front line on Russia and Afghanistan. The process of formulating and implementing the new strategy reflects a greater sectoral synergy and a more diversified policy method. At the same time，the multilateral mechanism represented by the United States and five Central Asian countries（C5+1）has been strengthened in political priority，field connotation and geographical extension，and has become an important platform for the United States to manage its relations with Central Asian countries. In the meantime，bilateral relations with fulcrum countries as the core are still the main way of US diplomacy towards Central Asia. In specific fields，regional governance has become a new concern of the United States. Biden administration will continue the basic framework of the new Central Asia strategy in the short term.